孤立性肺结节的临床与CT计量诊断

Clinical and CT quantitative diagnosis in solitary pulmonary nodule

目的探讨孤立性肺结节(SPN)的临床、CT计量诊断方法的准确性。方法收集145例经病理证实的SPN(原发性肺癌86例、良性肿瘤12例、结核球18例、炎性结节29例),采用最大似然法综合分析它们的年龄、性别、临床症状和HRCT或薄层CT征象(边缘形态、密度、周边特征),转化为评分值,判定结节所属类型。结果最大似然判别法对原发性肺癌、良性肿瘤、结核球、炎性结节的诊断正确率分别为91.9%、83.3%、72.2%、48.3%。平均判断正确率为80.0%。结论结合临床和CT指标的计量诊断法有助于鉴别SPN。

Objective To evaluate the accuracy of clinical and CT quantitative diagnosis in solitary pulmonary nodules （SPN）. Methods One hundred and forty-five cases with pathologically proved SPN （primary pulmonary carcinoma 86 cases, benign tumor 12 cases, tuberculoma 18 cases, inflammatory nodule 29 cases） were collected, we analyzed the age, sex, clinical symptom, and high-resolution CT or thin-slice CT signs （marginal contour, density, peripheral characteristic） and transferred them into scores by means of discrimination method of large log-likelihood to identify the category of SPN. Resuits The accuracy of diagnosis was 91.9% for primary pulmonary carcinoma, 83.3% for benign tumor, 72.2% for tuber- culoma and 48.3% for inflammatory nodule. The average accuracy of discrimination was 80.0%. Conclusion The method of clinical and CT quantitative diagnosis is helpful to differentiate SPN.