路优泰与氟西汀治疗抑郁症对照研究

Control study of neurostan and fluoxetine in treatment of patients with depression

目的:探讨路优泰对抑郁症患者的疗效及安全性。方法:将40例抑郁症患者随机分为路优泰组和氟西汀组,治疗6周。采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)和副反应量表(TESS)评定疗效和不良反应。结果:路优泰有效率为85%,对抑郁及伴随的焦虑症状作用明显,不良反应少而轻。结论:路优泰抗抑郁疗效肯定,与氟西汀相当,安全性好。

Objective：To study the efficacy and side effect of neurostan in the treatment of patients with depression. Method： 40 patients with depression were randomly divided into neurostan and fluoxetine for 6 weeks. The therapeutic response and side effects were evaluated with the Hamilton depressive scale（HAMD）,Hamihon anxiety scale（HAMA） and treatment emergent symptom scale（TESS）. Results：The efficacy rate of neurostan was 85%. Neurostan is markedly effective in the treatment of depression and anxiety symptom, with fewer and slight side effects. Condclusion： Neurostan is exactly effective in the treatment of depression, and efficacy is similar to that of fluoxetine, with fewer side effects.