2型糖尿病胃动力障碍的临床研究

Clinical analysis of gastric motility disorder in type 2 diabetes mellitus

[目的]应用胃电图(EGG)研究2型糖尿病(DM)胃动力的变化。[方法]选取2型DM患者60例,正常对照30例,对两组EGG的主频(FP)、振幅(AP)、胃动过缓百分率(B%)的变化与血糖的关系进行研究。[结果]DM组与正常对照组的空腹和餐后FP无统计学意义。两组餐后AP均显著高于空腹(P<0.05),但两组比较无统计学意义。两组餐前和餐后B%比较,DM组均明显高于正常对照组(P<0.05)。DM空腹血糖(FBG)与餐前、餐后B%呈正相关,随着FBG的升高,B%呈相关升高(P<0.01)。[结论]DM患者存在明显EGG异常,表现为胃动过缓明显增多的胃电节律紊乱。DM患者FBG与餐前、餐后B%呈正相关。

[Objective] To study gastric motility with electrogastrogram（EGG） in patients suffering from type 2 diabetes mellitus （DM） . [Methods] Sixty DM patients and thirty normal people were traced with EGG. Principal frequency（FP）, amplitude（AP）,percent of slow gastric motion（130/60）, and the relation of B% and fasting blood glucose（FBG） were analyzed. [Results] There was no significant difference in fasting and postprandial FP between the normal control group and the DM group. Postprandial amplitude was significantly higher than fasting amplitude in the two groups （P〈0. 05）. FBG was positive correlation with B% in fasting and postprandial （P〈 0. 01）. [Conclusion]EGG is obviously abnormal in type 2 DM patients, which characteristics is disorders of more slow gastric motion. FBG is positive correlation with B% in fasting and postprandial in type 2 DM patients.