溶胶凝胶法制备全丙基-β-CD气相色谱柱的涂渍机理初探

A Study on the Mechanism of 2,3,6-tri-O-Propyl-β-Cyclodextrin Capillary Gas Chromatographic Columns Prepared by the Sol-Gel Technology

用溶胶凝胶法制备了全丙基-β-CD气相色谱柱,得到了和对应静态柱相当的柱效,并和静态法色谱柱做了对G rob试剂和某些苯系位置异构体分离性能方面的比较.结果显示,这两种方法制备的毛细管气相色谱柱有相似的分离性能.初步探索了用溶胶凝胶法涂渍非端羟基固定相气相色谱毛细管柱的机理,说明了溶胶凝胶前体所形成的三维网状结构对固定相有裹挟作用,这种裹挟作用是固定相涂渍成功的关键因素.

2, 3, 6-tri-O-propyl-β-CD columns prepared by sol-gel technology are studied. Comparison of columns prepared by the sol-gel and by the static technology is carried out, showing that columns prepared by the two processes have similar capacities. The mechanism with which the non-hydroxy-terminated stationary phase columns are through the prepared sol-gel technology is discussed. It is seen that the sol-gel 3-D network can encapsulate the non-hydroxy- terminated stationary phase and that this encapsulation is a key factor in the preparation of sol-gel columns.