期刊文献+

肝部分切除术后P13K/Akt信号途径对肝窦内皮细胞功能的影响

Effect of phosphoinositide 3-kinase/ Akt-significance on the secretion function of rat SEC after partial hepatectomy
原文传递
导出
摘要 肝窦内皮细胞(HSEC)在一定条件下可以释放多种介质,如:肝细胞生长因子(HGF),转化生长因子β(TGF β),白细胞介素-6(IL-6),一氧化氮(NO)及一氧化氮合酶(NOS)等[1],这些细胞因子和介质在肝再生中发挥重要的作用.
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2005年第11期871-872,共2页 Chinese Journal of Hepatology
基金 国家自然科学基金(30070746)
关键词 肝切除术 信号传导 肝细胞生长因子 白细胞介素-6 肝窦内皮细胞 信号途径 PI3K 内皮细胞功能 一氧化氮合酶(NOS) Akt Hepatectomy Signal transduction Hepatocyte growth factor Interleukin-6 Hepatic sinusoidal endothelial cells
  • 相关文献

参考文献6

  • 1Malik R, Selden C, Hodgson H.The role of non-parenchymal cells in liver growth. Semin Cell Dev Biol, 2002, 13: 425-431.
  • 2Braet F, De Zanzer R, Sasaqki T, et al. Assessment of method of isolation, purification, and cultivation of rat liver sinusoidal endothelial cells. Lab invest, 1994, 70: 944-952.
  • 3Suzuki A, Iwama A, Miyashita H, et al. Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells. DeveloPment, 2003, 130: 2513-2524.
  • 4Selzner M, Camargo CA, Clavien PA. Ischemia impairs liver regeneration after major tissue loss in rodents: Protective effects of IL-6.Hepatology, 1999, 30: 469-475.
  • 5Dimmeler S, Fleming I, Fisslthaler B, et al. Activation of nitric oxide synthase in endothelial cell by Akt-dependent phosphorylation.Nature, 1999, 399: 601-605.
  • 6Higuchi H, Kurose I, Ebinums H, et al. Kuffer cell induces hepatocyte apPHtosis: Implication of nitric by fluorescence in situ hybridization. Hepatology, 1995, 22: 227A.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部