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金属硫蛋白在脑损伤中的作用 被引量:1

Role of metallothionein in treatment of brain injuries
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出处 《中华创伤杂志》 CAS CSCD 北大核心 2005年第11期878-880,共3页 Chinese Journal of Trauma
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  • 1Rigby KE, Stillman MJ. Structural studies of metal-free metallothionein. Biochem Biophys Res Commun, 2004, 325:1271-1278.
  • 2Jacob ST, Ghoshal K, Sheridan JF. Induction of metallothionein by stress and its molecular mechanisms. Gene Expr, 1999, 7:301-310.
  • 3Coyle P, Philcox JC, Carey LC, et al. Metallothionein: the multipurpose protein. Cell Mol Life Sci, 2002, 59:627-647.
  • 4Ono SI, Koropatnick DJ, Cherian MG. Regional brain distribution of metallothionein, zinc and copper in toxic milk mutant and transgenic mice. Toxicology, 1997, 124:1-10.
  • 5Choudhuri S, Kramer KK, Berman NE. Constitutive expression of metallothionein genes in mouse brain. Toxicol Appl Pharmacol, 1995, 131:144-154.
  • 6Penkowa M, Camats J, Giralt M, et al. Metallothionein-Ⅰ overexpression alters brain inflammation and stimulates brain repair in transgenic mice with astrocyte-targeted interleukin-6 expression. Glia, 2003, 42:287-306.
  • 7Chung RS, Adlard PA, Dittmann J, et al.Neuron-glia communication: metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury. J Neurochem, 2004, 88:454-461.
  • 8Penkowa M, Quintana A, Carrasco J, et al.Metallothionein prevents neurodegeneration and central nervous system cell death after treatment with gliotoxin 6-aminonicotinamide. J Neurosci Res, 2004, 77:35-53.
  • 9Kim D, Kim EH, Kim C, et al. Differential regulation of metallothionein-Ⅰ, Ⅱ, and Ⅲ mRNA expression in the rat brain following kainic acid treatment. Neuroreport, 2003, 14:679-682.
  • 10van Lookeren-Campagne M, Thibodeaux H, van Bruggen N, et al. Evidence for a protective role of metallothionein-Ⅰ in focal cerebral ischemia. Proc Natl Acad Sci USA, 1999, 96:12870-12875.

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