髋臼环状骨突生长速度的研究

The growth rate of acetabular ring apophysis: An experimental research

目的研究髋臼各组成部分环状骨突生长板的生长速度.方法选用年龄3～4周的新西兰大白兔20只,采用伸膝位长腿石膏管型固定的方法,将幼兔的左下肢固定8周,分别于固定后4、6、8周拍摄X线片直至出现髋臼发育不良兔动物模型7只.将分离出的发育不良髋臼制作病理组织学切片,运用图像分析技术量化髋臼发育不良动物模型中髋臼各组成部分(髂骨、坐骨、耻骨)的环状骨突生长板的生长速度.结果实验组发育不良的髋臼各骨中,坐骨环状骨突生长板生长速度最大,其次为髂骨,耻骨环状骨突生长板生长速度最低;对照组发育正常的髋臼各骨中,髂骨环状骨突生长板生长速度最大,其次为坐骨,耻骨环状骨突生长板生长速度最低.结论不同方向的力学刺激对髋臼各骨的生长发育具有重要影响.

Objective To investigate the growth rate of acetabular ring apophysis and explore the relationship between the growth rate and the acetabular dysplasia. Methods The animal model of acetabular dysplasia was established in 20 New Zealand white rabbits with left knee joint immobilization. Assessment of the acetabular status was made by serial X-rays in a reproducible standardized way. Eight weeks later, the tissues were collected from the experimental group and the controls to undergo histological analysis. Results In the control group, the maximal growth rate was detected in the ilium, then the ischium, and the minimal rate in the pubis. In the experimental group, however, the maximal growth rate was found in the ischium, and the minimal rate was noted in the pubis. Conclusions This study demonstrates that the direction of forces contributes to the growth rate of the growth plate in the acetabulum.