均匀设计法优化安息香单琥珀酸酯合成工艺研究

Study on the Optimum Conditions of Synthesis of Benzoic Homo-succinic Ester Using Uniform Design

用均匀设计法优化了安息香单琥珀酸酯的最佳工艺条件，得到第一步反应息安香的收率为８１．８５％，第二步反应安息香单琥珀酸酯的收率为９４．３５％。

The optimum conditions of synthesis technology of benzoic homo-succinic ester (BHSE) have been investigated using uniform design. It has been found that the yield of benzoic in first reaction would be reaching 81.85 %, the yield of BHSE in second reaction would be 94.35%.