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造血干/祖细胞凋亡机制研究进展 被引量：1

Research Progress of Haematopoietic Stem/Progenitor Cell Apoptosis
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摘要 造血干/祖细胞具有自我更新、增殖分化的潜能,机体的正常造血才得以维持,造血干细胞/祖细胞的增殖分化与细胞凋亡密切相关。凋亡的发生受凋亡相关基因调控。本文就引起造血干细胞/祖细胞凋亡机制研究进展做一综述。
作者 李宏颖 杨景春 刘文君 郭渠莲
机构地区 泸州医学院附属医院儿科 通辽市医院
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2005年第11期1145-1148,共4页 Journal of Applied Clinical Pediatrics
基金 四川省教委重点科研项目资助[川教科(1997-133)]
关键词 细胞凋亡 造血干细胞 研究
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
  • 相关文献

参考文献22

  • 1Fleury C, Mignotte B, Vayssiere JL. Mitochondrial reactive oxygen species in cell death signaling[J]. Biochimie, 2002,84 (2 - 3) : 131 -141.
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  • 4Xiao M, Oppenlander BK, Dooley DC. Transforming growth factor-beta(Ⅰ) induces apoptosls in CD34( + )CD38( -/low) cells that express Bcl-2 at a low level[J]. Exp Hematol, 2001,29(9):1098 - 1108.
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  • 8Yamaguchi H, Wang FIG. Bc1-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL[J]. J Biol Chem ,2002,277(44) :41604 -41612.
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二级参考文献13

  • 1刘文君,何政贤,林桂真,王清文.造血干细胞集落染色体SCE的制备[J].中华医学遗传学杂志,1996,13(2):112-113. 被引量：23
  • 2[1]de Boer F, Drager AM, Pinedo HM, et al. Early apoptosis largely accounts for functional impairment of CD34 + cells in frozen-thawed stem cell grafts. J Hematother Stem Cell Res, 2002; 11: 951-963
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  • 4[3]Baust JM, Vogel MJ, Van Buskirk R, et al. A molecular basis of cryopreservation failure and its modulation to improve cell survival.Cell Transplant, 2001; 10:561-571
  • 5[4]Stroh C, Cassens U, Samraj AK, et al. The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells. FASEB J, 2002; 16: 1651- 1653
  • 6[5]Peter AT, Linde-Forsberg C. Efficacy of the anticaspase agent zVAD-fmk on post-thaw viability of canine spermtozoa. Theriogenology, 2003; 59:1525 - 1532
  • 7[6]Eroglu A, Russo M J , Bieganski R, et al. Intracellular trehalose improves the survival of cryopreserved mammalian cells. Nat Biotechnol, 2000; 18: 163-167
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  • 9[8]Rauen U, Polzar B, Stephan H, et al. Cold-induced apoptosis in cultured hepatocytes and liver endothelial cells: mediation by reactive oxygen species. FASEBJ, 1999; 13:155-168
  • 10[9]Schulze-Osthoff K, Ferrari D, Los M, et al. Apoptosis signaling by death receptors. Eur J Biochem, 1998; 254:439-459

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实用儿科临床杂志
2005年 第11期

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