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DNA甲基化与口腔癌 被引量:2

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摘要 DNA甲基化是一种酶介导的DNA化学修饰过程,不改变DNA的一级结构。目前多认为是肿瘤抑癌基因失活的第三条途径,是当前肿瘤研究的热点领域。本文主要综述了DNA启动子CpG岛高甲基化导致抑癌基因失活与口腔癌的发生及其生物学行为之间的关系。
出处 《国外医学(口腔医学分册)》 2005年第5期353-355,共3页
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