Moyamoya病的临床表现与影像学特征分析

Study on clinical manifestations and imaging characteristics of 31 Moyamoya disease pateints.

目的总结Moyamoya病的临床及影像学特征. 方法回顾性分析南阳市1992年2月～2004年10月经DSA或MPA确诊的31例Moyamoya病患者的临床资料及影像学资料. 结果31例患者平均年龄25.7岁;脑卒中和头痛是本组Moyamoya病患者最常见的临床表现,发生率分别为83.9%(26例)和74.2%(23例);儿童及青少年患者以缺血性脑卒中发病为主,而成年患者以出血性脑卒中发病为主;所有患者均有颈内动脉或其分支狭窄或闭塞和Moy-amoya血管形成,其中有27例患者的CT或MRI表现为双侧病灶. 结论对于无脑血管病危险因素的年轻TIA或脑卒中患者,尤其有卒中史或反复头痛发作者则要考虑Moyamoya病的可能;MRA是诊断Moyamoya病的较好的无创检查手段.

Objective To study the clinical manifestation and imaging characteristics of Moyamoya disease. Methods Clinical data and imaging data of 31 patients with Moyamoya diease diagnosed by DSA or MRA were analyzed retrospectively. Results The mean age of the 31 patients was 25.7 years old. Stroke episodes and headaches were the main clinical manifestations with the occurrence rates of 83.9 % （26/31 ） and 74.2% （23/31 ）. All patients showed stenosis or occlusion of the internal carotid arteries or their branches and extensive abnormal basicranial vascular network called Moyamoya vascular, developed at the basal area of the brain. Conclusion It is suggested that there is a great possibility of occurrence of Moyamoya disease when recurrent stroke episodes or TIA or headaches occurred in young people. MRA is the reliable and noninvasive method of choice in diagnosis of Moyamoya disease.