老年腔隙性脑梗塞与血脂关系的研究

The study of the relationship between senile lacunar infarction and serum lipids levels

目的探讨老年腔隙性脑梗塞(LI)与脂质代谢的关系。方法检测110例老年LI患者血清血脂6项指标水平,并与对照组75例结果进行比较。TG、TC采用酶法,HDL-C采用选择遮蔽法,LDL-C采用化学修饰法,ApoA1、ApoB100采用免疫透射比浊法。结果老年LI组TG、TC、LDL-C、ApoB100水平显著高于对照组,HDL-C、ApoA1显著低于对照组,P均<0.05。结论老年LI患者存在脂质代谢紊乱,其中TG、TC、LDL-C及ApoB100水平与疾病呈正相关,HDL-C、ApoA1水平与疾病呈负相关。

Objective To study the relationship between lacunar infarction（LI） in old-age patients and metabolism of serum lipids. Methods TG, TC, HDL-C, LDL-C, ApoA1 and ApoB100 were measured in 110 old-age patients with LI and 75 old-age healthy person as control group. Results TG,TC,LDL-C and ApoB100 of old-age patients with LI were significandy higher than control group （P〈0.05）. HDL-C and ApoA1 of old-age patients with LI were significantly lower than control group （P〈0.05）. Conclusion Old-age patients with LI were found with serum lipids metabolism disorder. It has positive correlation between TG, TC, LDL-C, ApoB100 and LI. It has negative correlation between HDL-C, ApoA1 and LI.