摘要
目的:了解2型糖尿病患者血清抵抗素浓度与空腹血糖、血脂的关系。方法:选择50例2型糖尿病患者和50例健康中老年人,分别分为糖尿病组和非糖尿病组,用竞争性酶联免疫吸附法测定各组空腹血浆抵抗素水平,同时检测空腹血糖、血脂各项指标。结果:糖尿病空腹血浆抵抗素水平显著高于对照组(p<0.05)。抵抗素与甘油三脂、空腹血糖呈正相关关系(r=0.687,p<0.05,r=0.824,p<0.05),而抵抗素与其余各项血脂指标、性别之间无明显相关性。结论:血清抵抗素水平与2型糖尿病关系密切,抵抗素水平可能影响体内能量代谢和平衡,与糖代谢、脂代谢的关系更为密切。
Objective：To find out the relationship between the serum resistin levels and insulin resistance, blood-glucose as well as blood lipids in in the patients with type 2 diabetes. Methods： Senile patients （50） suffering from type 2 diabetes and non-diabetic control subjects were selected , Their serum resistin levels after an overnight fasting were measured by competitive ELSEA. Other date including blood-glucose, blood lipids. Results： The resistin level in the patients with type 2 diabetes was significantly higher than that of non-diabetic controls （p〈0.05）. Resistin levels showed a positive correlation with TG （ r = 0. 687, p〈0. 05）and blood-glucose （r = 0. 824, p〈0.05）. No correlation between resistin and fasting blood-glucose, other blood lipids and gender. Conclusions： The study results suggested that resistin maybe play a part in the type 2 diabetes. Resistin effect energy metabolism and blance , but resistin may be more closely correlated with glucose metabolism and lipid metabolism.
