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Changes of gastrointestinal myoelectric activity and bile acid pool during cholesterol gallstone formation in guinea pig 被引量:1

Changes of gastrointestinal myoelectric activity and bile acid pool during cholesterol gallstone formation in guinea pig
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摘要 It has been known that enterohepatic circulation of bile acids is essential for regular cycling of migrating motor complex (MMC). An important component of the enterohepatic circulation is the active reabsorption of conjugated bile acids in the terminal ileum, with special reference to bile acid pool size that may be defined as the total mass of bile acids in the enterohepatic circulation. However, because of technical difficulties in measuring of bile acid pool size in human being, the role of the bile acid pool has little been investigated, and the exact mechanism of change in bile acid pool size has not yet been clear. Therefore, were there two changes of small intestinal motility and bile acid pool size in cholesterol gallstone patients? and, if so, was there correlated relationship between both alterations require further investigation? It has been known that enterohepatic circulation of bile acids is essential for regular cycling of migrating motor complex (MMC). An important component of the enterohepatic circulation is the active reabsorption of conjugated bile acids in the terminal ileum, with special reference to bile acid pool size that may be defined as the total mass of bile acids in the enterohepatic circulation. However, because of technical difficulties in measuring of bile acid pool size in human being, the role of the bile acid pool has little been investigated, and the exact mechanism of change in bile acid pool size has not yet been clear. Therefore, were there two changes of small intestinal motility and bile acid pool size in cholesterol gallstone patients? and, if so, was there correlated relationship between both alterations require further investigation?
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2005年第18期1568-1571,共4页 中华医学杂志(英文版)
基金 ThisstudywassupportedbyagrantfromtheNationalNatural ScienceFoundationofChina(No.30170414).
关键词 cholesterol stone·enterohepatic circulation of bile acids·bile acid pool·migrating motor complex·gallbladder motility cholesterol stone·enterohepatic circulation of bile acids·bile acid pool·migrating motor complex·gallbladder motility
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