复发性外阴阴道假丝酵母菌病与个人行为、生活方式关系的探讨

Studies on relationship between recurrent vulvovaginal candidiasis and personal behavior and life style

目的探讨个人行为、生活方式与复发性外阴阴道假丝酵母菌病的关系。方法患复发性外阴阴道假丝酵母菌病的妇女72例,健康育龄妇女72例为对照,由专人做统一问卷调查,对调查结果做分析。结果经单因素非条件logistic回归分析,避孕(OR值=0·266)、勤换内衣(OR值=0·378)、行阴道灌洗(OR值=1·881)、与他人共用浴巾(OR值=1·872)、与他人互穿内衣(OR值=6·163)和吸烟(OR值=3·164)与复发性外阴阴道假丝酵母菌病呈统计学正相关(P<0·05);选取P<0·15标准,经多因素非条件logistic回归分析,避孕(OR值=0·219)、性生活频度(OR值=1·806)、使用无质量保证的卫生巾(OR值=1·844)、自行阴道灌洗(OR值=1·911)及吸烟(OR值=2·875)与复发性外阴阴道假丝酵母菌病的联系有统计学意义(P<0·05)。结论不良个人行为及生活方式是导致复发性外阴阴道假丝酵母菌病发生的重要因素,应该通过宣教,引导正确的个人行为和生活方式。

Objective To investigate the relationship between recurrent vulvovaginal candidiasis （RVVC） and personal behavior and life style. Method Seventy-two patients with RVVC and 72 normal healthy women were studied with questionnaire by case-control design. Results Analysis by univariate unconditional logistic regression showed that contraception （ OR = 0. 266 ） , frequently changing and washing one＇ s underpants （ OR = 0. 378 ）, vaginal douche （ OR = 1.881 ） , sharing bath towel with others （ OR = 1. 872）, sharing underpants with others （OR = 6. 163 ） and cigarette smoking or passive smoking （OR = 3. 164） were significantly associated with RVVC at significance level of 0.05. Analysis by multivariate unconditional logistic regression showed that contraception （OR = 0. 219） , frequency of sexual intercourse （ OR = 1. 806 ） , use of sanitary napkins without guaranteed quality （ OR = 1. 844 ） , self-vaignial douche （ OR = 1.911 ） and cigarette smoking or passive smoking （OR = 2.875 ） were associated with RVVC at significance level of 0. 15. Conclusions Poor personal hygiene and unhealthy life style were important factors attributed to RVVC. It is suggested to promote correct personal hygienic behavior and healthy lifestyle in women by health education in order to reduce RVVC.