小剂量多巴酚丁胺负荷超声心动图检测存活心肌临床研究

The value of low dose Dobutamine stress echocardiography in detecting survived myocardium

目的探讨小剂量多巴酚丁胺负荷超声心动图(LDDSE)预测存活心肌的价值。方法成功行冠状动脉血运重建(CRV)术的心肌梗死患者30例,CRV术前后分别行LDDSE及静息二维超声心动图(2-DE)检查。将试验时检出的功能改善节段与CRV术后相应节段收缩功能改善与否的实际情况对比,计算LDDSE识别存活心肌的敏感性、特异性、准确性。结果多巴酚丁胺(Dob)5、10μg/(kg·min)2-DE的敏感性分别为73·0%,89·6%;特异性分别为81·7%,82·8%;准确性分别为76·9%,86·5%。结论LDDSE是一种安全、简便、经济可广泛应用的预测存活心肌的有价值的方法。

Objective To assess the value of low-dose dobutamine stress echocardiography（LDDSE） for detecting survived myoeardium in patients with myoeardioal infarction （MI） .Meflaods In 30 patients with MI,who were scheduled to undergo successfially coronary revascularization（CRV）, rest 2 - DE and LDDSE test were conducted within a week before CRV, and the follow - up 2 - DE were also done about 1 - 3months after CRV. The sensitivity, specificity, and accuracy of the LDDSE tests for indentifying viable myocardium were calculated by comparing with the post-CRV actual contractile improvement of corresponding segments. Results The sensitivity of dobutamine （Dob） 5,10ug/kg.min 2 - DE test was 73.0%and 89.6% respectively. The specificity of them was 81.7% and 82.8 % respectively; the accuracy of them was 76.9% and 86.5 % respectively. Conclusion LDDSE is a simple , cost-effective, widely available method to identify viable myocardium in the patients with MI.