益生菌产品活菌数与保健效果关系之研究

The Relation between Probiotics’s Live Cultures and Health Function

益生菌对人体功效是否一定以活菌为主要指标,过去有若干争议。但是经过科学论证,益生菌功效必须以活菌为先决条件,应该已经成为定论。本文就相关原理及数据探讨了活菌与对益生菌功效的关系以及保健食品应该含有的适当活菌数量。基本上有竞争力的保健食品益生菌应该具备下列条件:(1).活菌含量于常温状态储存12个月后能达每克1×109cfu以上;(2).能有多种不同菌株供选择调制配方以适应不同市场需求;(3).能通过胃肠各种不利条件之考验,耐酸,不易被胆汁消化等;(4).能在大肠中发挥双歧杆菌的功效,添加菌量至少达1×109cfu/g,并有足够寡糖或其它助生素供其繁殖。

Probiotics have been debated in China regarding the merit of live cultures against dead cultures. It seems that the subject should be settled from the perspective of activity principle. The mechanism of action, as well as the principle of product formulation will determine the success or failure ofa probiotic product. The following conditions for a successful health food product include： （1）.live culture shall be more than 1 × 10^9cfu/ml or g, （2）.Multiple choice of cultures for formulation, （3）.The culture should be strengthened to survive the harsh conditions in stomach and intestine, （4）. The culture designed for colon health, such as Bifidobaterium sp., should be formulated with probiotics so that it could achieve 1 × 10^9 cfu/g through localized propagation.