摘要
目的观察扶正通脉胶囊治疗急性期脑梗死的临床疗效,并研究其作用机制。方法选择81例符合中医辨证属气虚血瘀、痰阻络痹并经头颅CT确诊为急性期脑梗死的病人,随机分为治疗组(51例)和对照组(30例)。治疗组服用扶正通脉胶囊,对照组服用络欣通,连续治疗28d观察疗效。结果治疗组总有效率94.12%,对照组总有效率93.33%,两组比较无统计学意义(P>0.05),但治疗组愈显率(74.51%)明显高于对照组(40.00%,P<0.05)。病人神经功能缺损恢复程度及血液流变学指标改善等方面,治疗组均优于对照组(P<0.05或P<0.01)。服药过程中及服药后未见药物不良反应。结论扶正通脉胶囊对气虚血瘀型、痰阻络痹脑梗死急性期具有良好的治疗效果,并能改善血液流变学指标,降低血液黏稠度,改善脑部症状区血液循环,促进受损脑细胞功能恢复,降低病残率,提高生存质量。
Objective To observe the effect of Fuzhengtongmai (FZTMC) Capsules(FZTMC) on acute cerebral infarction(ACI) with Qi deficiency and blcod stasis,phlegm stagnation and collaterals bi(TCM). Methods Eighty- one patients with acute cerebral infarction( Qi deficiency and blood stasis, phlegm stagnation and collaterals bi - syndrome diagnosis by TCM) were divided into two groups randomly: Treatment group(TG, n = 51 ) treated by FZTMC and control group (CG, n = 30) treated by Luoxintong for 28 days. Results The total effective rate was 94.12 % in the treatment group and 93.33 % in the control group respectively(P 〉 0.05). The marked effective and cure rate was higher in TG(74.51% ) than that in CG(40.00% ). The recovery degree of neurological deficit and the improvement of blood rheology were better in TG than that in CG( P 〈 0.05 or P 〈 0.01). No side - effects were found. Conclusion The results show that FZTMC Could promote the functional recovery of damaged cerebral cells and decrease the disability rate.
出处
《中西医结合心脑血管病杂志》
2005年第10期863-865,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
脑梗死
急性期
扶正通脉
络欣通
cerebral infarction, acute
Fuzhengtongmai, capsules
Luoxintong