HIV-1感染中第二受体与艾滋病进程的关系
The relation between coreceptor use and progression of AIDS in HIV-1 infection
摘要
第二受体在HIV_1感染及病程变化中有着重要作用,HIV_1所利用的第二受体由CCR5转换为CXCR4被认为是病程进展的标志,而X4型HIV_1也与较差的预后相联系。但是近几年的研究使人们对这种第二受体利用的转换有了新的认识,在近半数HIV_1感染者体内并不发生这种转换,但他们大多数会进展为艾滋病。本文就这一问题作了综述。
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共引文献3
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