期刊文献+

大豆异黄酮雌激素样作用与骨质疏松的防治 被引量:10

The estrogen-like effects of soybean isoflavones and the treatment of osteoporosis
下载PDF
导出
摘要 此文综述了近年来大豆异黄酮防治骨质疏松作用的研究进展。大豆异黄酮作为一种植物雌激素可模拟雌激素作用于骨骼系统,调节骨吸收和骨形成,有防治骨质疏松的作用。同时,大豆异黄酮与雌激素作用又有不同,如对子宫等生殖器官作用小,有降低肿瘤及心血管病发生风险等有益作用,故值得进一步研究大豆异黄酮药理作用机制。
出处 《中国生化药物杂志》 CAS CSCD 2005年第5期312-314,共3页 Chinese Journal of Biochemical Pharmaceutics
  • 相关文献

参考文献20

  • 1Takahashi N, Akatsu T, Udagawa N, et al. Osteoblastic cells are involved in osteoclast formation [ J ]. Endocrinology, 1988, 123(5):2600-2602.
  • 2Anderson DM, Maraskovsky E, Billingsley WL, et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function [ J ]. Nature, 1997,390(6656): 175-179.
  • 3Wang H J, Murphy PA. Isoflavone composition of American and Japanese soybeans in lowa: effects of variety crop year and location [ J ]. Agric Food Chem, 1994,43(2): 1674-1679.
  • 4Ross PD, Norismatsu H, Davis TW, et al. A comparison of hip fracture incidence among native Japanese, Japanese Americans, and American Caucations [ J ]. Am J Epidemiol, 1991,133(8): 801-809.
  • 5Pichert C, Bennetau PC, Chanteranne B, et al. Soybean isoflavone dosidependently reduce bone turnover but do not reverse established osteopenia in adult ovariectomized rats [ J ]. J Nutr, 2001,131(3):723-728.
  • 6Alekel DL, Germain AS, Peterson CT, et al. Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of periminopausal women[J]. Am J Clin Nutr,2000,72(3):844-852.
  • 7Arjmandi BH,Birnbaum K,Goyal NV, et al. Bone-sparing effect of soy protein in ovarian-hormone-deficient rats is related to its isoflavone content[J]. Am J Clin Nutr, 1998,68(Suppl): 1364-1368.
  • 8Ishida H, Uesugi T, Hirai K, et al. Preventive effects of the plant isoflavone, daidein and genistcin on bone loss in ovariectomized rats fed a calcium-deficient diet[ J ]. Biol Pharm Bull, 1998,21(1): 62-66.
  • 9Ishimi Y, Arai N, Wang XX, et al. Difference in effective dosage of genistein on bone and uterus in ovariectomized mice [ J ]. Biochem Biophys Res Commun,2000,274(3):697-701.
  • 10An J, Tzagaradis-Foster C, Scharschmidt TC, et al. Estrogen receptor beta-selective transcriptional activity and recruitment of coregulators by phytoestrogens [ J ]. J Biol Chem, 2001,276(21): 17808-17814.

同被引文献141

引证文献10

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部