1Petruzzelis V,Troccoli T, Candiani C, et al. Oxerutins(venoruton):efficacy in chronic venous insufficiency [a double-blind, randomized,controlledStudy] [J]. Angiology, 2002,53(3): 257-263.
2Cosarane MR, Belcaro G, Geroulakos G, et al. Flight microangiopathy on long-haul flights: prevention of edema and microcirculation alterations with venoruton [ J ]. Clin Appl Thromb Haemost, 2003, 9(2):109-114.
3Unkauf M, Rehn D, Klinger J, et al. Investigation of the efficacy of oxenrutins compared to placebo in patients with chronic venous insufficiency treated with compression stockings [J]. Arzneimittelforschung, 1996,46(3):478-482.
4Rehn D, Brunnauer H, Diebschlag W, et al. Investigation of the therapeutic equivalence of different galenical preparations of O-(beta-hydroxyethyl)-rutosides following multiple dose peroral administration[ J ]. Arzneimittelforschung, 1996,46(3): 488-492.
5Bergstein NAM. Clinical study on the efficacy of O-(beta-Hydroxyethyl)-Rutoside (HR) in varicosis of pregnancy[J]. J Int Med Res, 1975,3(2):189-193.
6Wadworth AN, Faulds D. Hydroxyethylrutosides. A review of its pharmacology, and therapeutic efficacyin venous insufficiency and related disorders [ J ]. Drugs, 1992,44(8): 1013 - 1033.
7Wijayanegara H, Mose JC, Achmad L, et al. A clinical trial of hydroxyethylrutosides in the treatment of hemorrhoids of pregnancy[J].J Iht Med Res, 1992,20(1): 54-60.
8Sumboonnanonda K, Lertsithichai P. Clinical study of the Ginko biloba-Troxerutin-Heptaminol Hce in the treatment of acute hemorrhoidal attacks[J] .J Med Assoe Thai,2004,87(2):137-142.
9Mortimer PS, Badger C, Clarke, et al. A double-blind, randomized, parallel-group, Placebo controlled trial of O-(beta-Hydroxyethyl)-Rutosides inchronic arm oedema resulting from breast cancer treatment[J]. Phlebologie, 1995,10(1):51-55.
10Riccioni C, Sarcinella R, Izzo A, et al. Effectiveness of troxerutin in association with Pycnogenol in the treatment of acute hemorrhoidal attacks[J].J Med Assoc Thai,2004,52(1):43-48.
