颅内血肿微创术对脑室出血病死率的影响

Minimally invasive surgery to the influence of death rate resulted from the ventrilular hemorrhage

目的:观察颅内血肿微创术并用尿激酶灌注冲洗对脑室出血病死率的影响。方法:30例脑室出血患者随机分成微创术尿激酶灌注组和对照组。观察30d病死率,计算其30d的预测病死率,并进行比较。结果:30例患者平均脑室出血量为(45.17±23.12)m l,有13例合并脑内血肿的平均出血量为(8.17±5.52)m l。发病30d内死亡8例(26.67%),其中微创组死亡2例(13.3%),对照组死亡6例(40%),显著低于其预测病死率(66.13%)。结论:微创术并用尿激酶灌注冲洗可显著降低脑室出血患者30d内的病死率,且有效、安全。

Objective： To observe the minimally invasive surgery to the influence of the death rate resulted from the ventrilular hemorrhage. Methods： 30 patients with ventrilular hemorrhage were randomly assigned to receive urokinase injection or placebo. 30 days death rate,30 day mortality were compared with predicted 30 day mortality. Results：Mean intraventricular hemorrhage volume was （45.17±23.12）ml in 30 patients,with mean intracerebral hrmorrhage of （8.17±5.52）ml in 13 of them. 8 patients （26.67%） died within 30 days, and the mortality was signficant lower （P〈0. 001） than that,of predicted （66. 13%） of these patients. Conclusion： The minimally invasive surgery plus intraventricular urokinase may significantly decrease 30 day mortality of patients with intraventricular hemorrhage apears to be valid and safety.