摘要
目的分析卵巢上皮癌淋巴结转移情况,同时结合血清CA_(125)检测,为临床判断肿瘤性质,选择正规治疗及预后的预测提供科学依据。方法收集93例卵巢上皮癌患者的病例资料,回顾性分析淋巴结转移的情况,同时对治疗前后患者行血清CA_(125)检测。结果93例卵巢上皮癌淋巴结转移率为55.9%,Ⅲ期淋巴结清扫与未清扫5年生存率分别为87.5%和38.1%,差别有显著性意义(P<0.01)。24例Ⅲ期患者行盆腔、腹主动脉旁、腹膜后淋巴结清除术,且术后经正规化疗者CA_(125)浓度明显下降,监测5年CA_(125)阳性率16.7%,而21例未经淋巴结清除术患者中监测5年CA_(125)阳性率47.6%,差异有显著性(P<0.05)。结论对卵巢上皮癌患者采用淋巴结清除术很有必要并越早越好,同时监测治疗后患者血清CA_(125)浓度,二者的结合对临床正规治疗以及治疗效果和患者的预后判断均具有重要意义。
Objective To analyze conditions of lymph nodes metastasis and combine examining of CA125 in blood serum,in order to judge king of tumors in clinic ,and to excerpt normal therapy and predict prognosis for providing scientific basis.Methods Datas of 93 cases ovarian neoplasm were captured ,and studied retrospectivly effective agents of lymph nodes metastasis ,and examined patiens of preftratment and post-treatment CA125 in blood serum.Results Lymph nodes metastasis rate was 55.9% in 93 cases ovarian neoplasm;The 5-year surival rates were 87.5% and 38.1% for stage Ⅲ kcases with lymphadendctomy and non-lymphadenectomy,the diffenece was significant （X^2=11.5262,P〈0.01）.CA125 concentration was phanero-descent in 24 cases of stage Ⅲ with pelvic kidney ,para-abdormial aorta,retroperitoneal lymphadnectomy and normal chemo-treatment;Through examining CA125 positive ration was 16.7% in five years,but CA125 positive ration was 47.6% for cases with non-lymphadenectomy in five years ,the difference was significant （X^2=5.0087,P〈0.05）.Conclusions It is necessary for patiens of ovarian neoplasm to adopt lymphade-nectomy,and the earlier,the better,and combine examining of post-treatment CA125 in blood serum;Combining the two factors is important for nmrmal clinical therapy to judge therapeutic efficacy and prognosis.
出处
《潍坊医学院学报》
2005年第5期334-336,共3页
Acta Academiae Medicinae Weifang
