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TRAIL在胃癌中的表达及其意义 被引量:3

Expression and clinical significance of TRAIL in gastric carcinoma
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摘要 应用免疫组织化学SP法检测4 0例胃癌、1 4例胃平滑肌瘤和1 0例良性胃病组织中肿瘤坏死因子相关的凋亡诱导配基(TRAIL)的表达,并与临床病理参数进行相关性分析。结果示:TRAIL在胃癌、胃平滑肌瘤和良性胃病组织中的表达率依次为3 5.0%,7 1.4%,8 0.0%;TRAIL的表达与胃癌患者的性别、年龄、肿瘤部位无关(P>0.0 5),与胃癌细胞的生物学行为有关(P<0.0 5);TRAIL的表达与胃癌患者的预后有一定关系,其表达高者预后较好。提示TRAIL可能在胃癌的发生、发展和预后方面起一定的作用。
出处 《中国普通外科杂志》 CAS CSCD 2005年第10期789-791,共3页 China Journal of General Surgery
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