胃肠道间质瘤(附25例临床分析)

Clinical Analysis on Gastrointestinal Stroma Tumor

目的胃肠道间质肿瘤是消化道最常见的间叶组织来源的肿瘤,本文旨在提高对该病的认识,减少术前误诊率及在临床诊治中作出合理的决策.方法收集南京医科大学附属淮安医院1995-08～2004-10间手术后病理确诊病例25例,作回顾性研究.结果本组病变在胃部16例,占64%;小肠5例,占20%;直肠、食管各占8%;胃间质瘤行肿瘤切除占18.8%,行胃大部切除占25%,行根治术占56.2%.其中,2例食管病变行肿瘤剥除术,2例直肠病变均行Miles术.结论该病术前确诊率较低,对胃肠道占位性病变要警惕该病的发生,结合内窥镜、螺旋CT与X线钡餐检查及B超检查,有助于提高术前确诊率.因此,应根据肿瘤大小、性质、部位、年龄及全身状况决定术式.

Objective To improve the awareness, reduce tbe misdiagnosis rate and find reasonable treatment of gastrointestinal stroma tumor （GIST） . Methods The clinical materials of 25 cases that obtained diagnosis in pathology were analyzed retrospectively from August 1995 to October 2004. Results In this group, there were 16 cases tumor in stomach, 5 cases in small intestine and 2 cases in esophageal and rectal tumor per each. There was about 18.8% of tumor resection, 25% of subtotal gastrectomy and 56.2% of radical gastrectomy. The tumor resection was performed in esophagus and miles operation was performed in rectal intestine. Conclusion The diagnostic rate was lower before operation. The combination of detections might be helpful, to obtain the accuracy diagnosis. The operation should be performed according to age, location, size and general condition.