2型糖尿病下肢血管病变相关因素分析

Analysis on correlated factors of type 2 diabetes mellitus with complication of lower extremities vascular lession

目的:探讨2型糖尿病患者并发下肢血管病变的各种相关因素。方法:对74例2型糖尿病患者进行下肢血管彩色多普勒超声检查,同时测定空腹血糖(FBG)及餐后2h血糖(2h-PBG)、收缩压(SBP)、舒张压(DBP)、糖化血红蛋白(HbAlc)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及空腹胰岛素水平等,并分析上述指标与糖尿病下肢血管病变的关系。结果:糖尿病并发下肢血管病变与病程、SBP、DBP及HbAlc、空腹胰岛素水平、LDL-C明显相关。结论:为防止糖尿病下肢血管病变的发生,应尽早诊断,积极控制高血糖、高血脂、高血压及高胰岛素血症等危险因素。

Objective： To evaluate the correlate factors influencing type 2 diabetes mellitus with complication of lower extremities vascular lession. Methods： Seventy-four patients with type 2 diabetes mellitus were measured in lower extremities by Doppler Uhrasonography. The basical informations about patients were recorded. Fasting blood glucose, 2 hours postprandial blood glucose, systolic pressure, diastolic pressure, glycosylated hemoglobin, triglycerides, total cholesterot, high density lipoprotein-C, low density lipoprotein-C and fasting blood insuline were examined,which were applied to analyze the relations with type 2 diabetes mellitus with complication of lower extremities blood vessel lesion. Results： The diabetes patients complicated lower extremities blood vessel lesions were significantly correlated with the length of lesion, systolic pressure, diastolic pressure, glycosylated hemoglobin, fasting blood insuline, low density lipoprotein-C. Conclusions： To prevent the occurrence of diabetes with complication of lower extremities blood vessel lesion, we should establish diagnosis as early as possible and activetly control hyperglycosemia, hyperlipidemia, hypertension and hyperinsulinemia.