脾破裂术后血小板增多18例临床分析

Clinical analysis of 18 cases with increased platelets after the operation for spleen rupture

目的探讨脾破裂术后血小板增多的过程和处理.方法对18例脾破裂行脾切除术后血小板升致520～790×109/L患者的临床资料进行分析总结.结果18例患者术后第二天血小板逐渐增多,术后1～2周达到高峰值.血小板＞380×109/L时开始用药,用药约3周后均降至正常水平.结论对外伤性脾破裂患者应尽量采用保脾手术,脾切除术后血小板＞380×109/L时应考虑使用药物预防静脉血栓形成.

Objective To inquire into the procedure and treatment of the platelets increase after the operation for spleen rupture. Methods The clinical data of 18cases, whose platelets increased to 520- 790 ×10^9/L after the operation for spleen rupture, were retrospectively analyzed. Results Of the 18 cases, the platelets began to increase at the second day after the splenectomy and got to the peak values at the 1- 2 weeks after the operations. When the platelets increased to over than 380 ×10^9/L, corresponding treatment were adopted, and the platelets decreased to normal level after 3 weeks of the treatment. Conclusion The spleen-reserving splenectomy should be adopted as far as possible to the cases with traumatic spleen rupture. When the platelets increased to over than 380 ×10^9/L after the splenectomy, corresponding treatment should be applied to prevent venous thrombosis.