围术期高血压脑出血患者的血清T_3、T_4测定临床研究

Clinical study on determination of serum T_3、T_4 in patients with hypertensive cerebral hemorrhage during perioperative period

目的探讨围术期高血压脑出血患者血清T3、T4动态变化及临床意义。方法采用同位素放射免疫分析法测定28例高血压脑出血患者术前、术中、术后的T3、T4含量并与正常对照组作比较。结果入院时脑出血量<30ml,T3、T4值均较正常对照组有明显差异(P<0.05),并随着治疗的康复,此种变化渐恢复。入院时脑出血量≥30ml,T3值明显低下。结论动态检测高血压脑出血患者血清甲状腺激素水平变化,对判断患者病情发展、预后具有重要的临床价值。

Objective To explore the clinical significance and dynamic change on determination of serum T3,T4 of hypertensive cerebral hemorrhage during perioperative period. Methods From March 2003 to March 2005,the level of T3、T4 were detected by radioimmunoassay in 28 cases with hypertensive cerebral hemorrhage during perioperative period and compared with normal control group.Results In the patients with cerebral bleeding volum 〈 30ml, T3,T4 values had obvious difference comparing with the control group（all P 〈 0.05）,but they were recovered gradually along with curative process. There were no significant differences compared to control group （P 〉 0.05）. When cerebral bleeding volum≥ 30ml, serum T3 value was decreased obviously on admission. Conclusion There is important clinical significance to judge the clinical development and prognosis by determing the dymamic change of serum thyroxine level for patients with hypertensive cerebral hemorrhage.