超声引导射频治疗大肠癌肝转移

Ultrasound-guided radiofrequency ablation in the treatment of liver metastases of colorectal carcinoma

目的探讨超声引导射频治疗大肠癌肝转移的临床疗效。方法对近5年不能手术治疗的大肠癌肝转移患者24例(50个病灶)行超声引导射频治疗。结果治疗后1个月复查彩色超声多普勒血流显像(CDFI)或CT增强扫描,显示46个病灶完全灭活,有效率达92%,6例患者肝内其它部位再发,行第2～4次治疗,全部病例经3～24个月随访,存活20例。并发症包括治疗区胀热感、疼痛和轻度发热。结论超声引导射频治疗大肠癌肝转移具有创伤小、疗效好、并发症少、可反复治疗等优点。

Objective To study the clinical efficacy of ultrasound-guided radiofequency ablation（RFA） in the treatment of liver metastases of colorectal carcinoma. Methods In the recent 5 years,24 patients （50 liver metastatic lesions）,who were not appropriate candidates for resection were treated with RFA. Results 46 lesions were completely ablated according to the results of contrast-enhanced CT or CDFI 1 month after the RFA （effective rate,92%）. There were 6 patiens with multi-focal recurrences in the liver,and treatment of 2^th - 4^th times of RFA were performed necessarily.All patients were follew up from 3-24 months, 20 patients were alive to date.The complications included swell-heat feeling in the treatment area, pain and low fever. Conclusion Ultrasoundguided radiofrequency ablation is a minimally-invasive and effective technique with low complications in the treatment of liver metastases of colorectal carcinoma.h can be performed for several times on those recurrent lesions.