脉冲电磁场治疗原发性骨质疏松近期疗效观察

Shortterm effect of pulsed electro-magnetic fields on management of osteoporosis

目的观察脉冲电磁场对原发性骨质疏松患者的骨密度及生化指标的改善情况。方法治疗组采用Union2000型骨质疏松治疗系统联合钙尔奇D片,治疗共60d,而对照组采用钙尔奇D片,连用60d。治疗前后分别测定骨密度、血骨钙素、尿羟脯氨酸和临床腰背痛评分,测定结果用SPSS软件,分别进行组内和组间比较。结果①对照组治疗前后骨密度(L2L4)无明显变化,治疗组治疗后与治疗前比较骨密度有所增加,但无统计学意义;②对照组治疗前后临床腰背痛评分无明显差异,治疗组治疗后临床腰背痛评分较治疗前明显增加;③对照组治疗前后血骨钙素无统计学差别,治疗组治疗后骨钙素水平较治疗前明显升高;④对照组治疗前后尿羟脯氨酸浓度无统计学差异,治疗组治疗前后尿羟脯氨酸无统计学差异。结论脉冲电磁场治疗原发性骨质疏松在缓解临床骨痛症状方面效果十分显著,并且能够明显提高患者的骨形成速率,而对骨吸收速率无明显影响。但本研究观察脉冲电磁场中对骨密度无明显改善,这可能是与随访时间较短有关。

Objective To find out the effect of pulsed electro-magnetic fields（PEMF） on osteoporosis. Methods The treatment group received therapy of Union-2000 osteoporosis treatment system. Both of the treatment and control group were given ealtrate-D for 60 days. BMD, plasma BGP, urinary HOP and clinical waist and backache grade were determined before and after the course. Results 1. The BMD urinary Hop in both groups had significant increase after treatment;2. In the treatment group, the clinical waist, backache grade and the plasma BGP were higher than that before treatment and no difference was shown in the controls. Conclusions PEMF may improve bone formation and relieve clinical symptoms,but has no effect on bone resorption.