摘要
目的探讨食管癌患者放疗前后血清TSGF水平变化的临床价值。方法用TSGF诊断试剂盒检测并动态观察食管癌患者放疗前后TSGF水平变化。结果57例食管鳞癌患者放疗前血清TSGF平均值为67.7±1.6U/ml,显著高于健康对照组(t=6.822P=0.000);22例有纵隔或(和)颈淋巴结转移的患者与无淋巴结转移者35例比较,血清TSGF均值分别为77.2±2.3U/ml和62.4±1.6U/ml,t=5.399,P=0.000;放疗前后血清TSGF值持续阳性者或血清TSGF值由阴性转为阳性者1年内复发转移率明显增高(P<0.05)。结论食管癌放疗前后血清TSGF水平的动态变化是监测肿瘤复发转移的重要指标。
Objective To explore the clinical value of dynamic change of serum TSGF levels in patients with esophageal carcinoma （EC）treated with radiotherapy. Methods The serum levels of TSGF in 57 patients with EC before and after radiotherapy were detected by TSGF diagnostic kits. Results The serum levels of TSGF in 57 patients were significantly higher than those of control group （67.7±1.6U/ml Vs 56.6±5.8U/ml, P=0. 000） ; In group with mediastinum or （and） neck lymph nodes metastasis and those without lymph nodes metastasis, the serum levels of TSGF were 77.2±2.3U/ml and 62.4±1.6U/ml respectively （t=5.399, P=0.000）. After radiotherapy, the patients of serum TSGF positive had more recrudesce rate than those of serum TSGF negative in one year （P〈0.05）. Conclusion Dynamic change of serum TSGF levels in patients with EC before and after radiotherapy is an important marker in monitoring recurrence and metastasis of carcinomas.
出处
《中国现代医药杂志》
2005年第5期11-13,共3页
Modern Medicine Journal of China
