摘要
以三氯硫磷、苯唑醇、6-氨基己酸为原料,采用三步反应,合成三唑磷半抗原6-[O-乙基-O-（1-苯基-1H-1,2,4-三唑-3-基）硫代磷酰胺基]己酸,经质谱和1H-NMR鉴定表明合成成功,为进一步制备三唑磷抗体奠定了基础.
This paper reported hapten synthesis and identification of the organophosphate pesticide triazophos. Thiophosphoryl chloride and phenylzole alcohol and 6-aminocaproic acid were employed as the main reactants to synthesize the triazophos hapten 6-（ethoxy （1-phenyl-1H-1,2,4-triazol-3-yloxy）phospho-rothioy-lamino） hexanoic acid, the product were confirmed by MS and 1H-NMR. The result showed that the hapten synthesis strategies and condition is suitable and will be contributed to antibody preparation.
出处
《农产品加工（下）》
2005年第9期21-24,共4页
Farm Products Processing
基金
国家自然科学基金（20477012）
广东省自然科学基金重点项目（036842）.
关键词
三唑磷
半抗原
合成
鉴定
triazophos
hapten
synthesis
identification
