硝普钠、多巴胺联合治疗顽固性心力衰竭临床分析

Treatment of Obstinate Heart Failure by Combined SodiumNitroprusside with Dopamine

目的:观察硝普钠联合多巴胺治疗顽固性心力衰竭的疗效。方法:选择顽固性心力衰竭住院患者26例,心功能Ⅲ级21例,心功能Ⅳ级5例,入院后在常规治疗基础上加用硝普钠,从10μg/min开始,根据血压逐渐调量。多巴胺从1μg/kg·min开始,根据血压调量,一般用量2.5μg/kg·min,最大12μg/kg·min,疗程7±2天。结果:显效6例(23.08%),有效17例(65.48%),无效3例(11.44%),总有效率88.56%。结论:硝普钠联合多巴胺对顽固性心力衰竭有明显治疗作用。

Objective： To observe the effects of SodiumNitmprusside and Dopamine on hemodynamics in hert dysfunction. Methods： Twenty-six obstinate Heart failure 21 functional class Ⅲ, 5 functional class Ⅳ, were taken SodiumNitroprusside injection（ 10μg·min^-1 ）and were taken Dopamine injection（2.5μg·kg^-1·min^-1 ）, total period of treatment was mean 7±2 day. Results： 6 remarkably cases（23.08 % ）, 17 availability cases（65.48 % ）, 3 inefficacy cases（ 11.44 % ）, aggregate efficiency rate is 88.56 %. Conclusion：SodiumNitroprusside combine with Dopamine injection can improve cardiac functionof cases with obstinate heart failure.