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溶栓导管治疗下肢深静脉血栓形成的临床应用 被引量:24

Clinical application of infusion catheter-directed thrombolysis for deep venous thrombosis in lower extremities
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摘要 目的评价溶栓导管治疗下肢深静脉血栓形成(DVT)的疗效。方法2003年4月~2004年10月,32例左下肢DVT患者施行了溶栓导管置入术,采用抗凝及经溶栓导管脉冲式灌注尿激酶治疗。其中行下腔静脉滤器置入术11例、行髂总静脉球囊扩张术10例,行髂总静脉支架置入术2例。结果溶栓导管平均放置时间为(7.7±2.3)d。下肢水肿完全消退28例,部分消退4例。左下肢深静脉血栓完全溶解29例,其中12例存在左髂静脉受压综合征;血栓部分溶解3例。无出血、肺动脉栓塞等并发症。结论采用溶栓导管治疗下肢DVT是一种安全、有效的方法。 Objective To investigate the effectiveness of infusion catheter-directed thrombolysis for deep venous thrombosis in lower extremities. Methods Between April 2003 and October 2004, thirty-two patients with deep venous thrombosis of left lower extremities underwent infusion catheter-directed thrombolysis with urokinase and anti-coagulation, among which 11 cases were treated with placement of inferior vena cava filters, 10 with percutaneous transluminal angioplasty of left common iliac veins and 2 with stents placed in the common iliac veins. Results Average time of infusion catheter placement was (7.7±2.3) days. Edema of diseased limbs subsided completely in 28 patients and partially in 4. Complete thrombolysis of left lower extremity deep veins was achieved in 29 patients including 12 cases with left iliac venous compression syndrome, and partial thrombolysis in 3 patients. There were no complications of hemorrhage or pulmonary embolism. Conclusions Infusion catheter-directed thrombolysis of lower extremity deep venous thrombosis is a safe and effective method.
出处 《介入放射学杂志》 CSCD 2005年第5期487-489,共3页 Journal of Interventional Radiology
基金 江苏省科技发展计划项目(课题编号:BS200309)
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