毒死蜱中间体三氯吡啶酚的合成

The Synthesis of 3,5,6-Trichloro-2-pyridinol

选择吡啶路线合成了毒死蜱的中间体三氯吡啶酚。以吡啶为原料,经氯化、还原及水解3步反应得到目标化合物,含量、收率均达到92.5%。

3,5,6-trichloro-2-pyridinol is an important intermediate of chlorpyrifos. Using pyridine as starting material, the desired compound was synthesized through chlorination, reduction and hydrolysis. The content and yield of the product all attain 92.5%.