摘要
间溴苯甲醚与2-二甲胺甲基环己酮反应,在一定的条件下制备得到1-间甲氧苯基-2-二甲胺甲基环己醇的顺反异构体的混合物,对其分离得到相应地反式异构体——盐酸曲马多。
The reaction of m-bromoanisole with 2-(dimethylaminomethyl)cyclohexanone yielded the title as a mixture of Z- and E-isomers,which were separated into tramadol.
出处
《河北化工》
2005年第5期36-36,78,共2页
Hebei Chemical Industry