西沙必利和小剂量红霉素治疗早产儿喂养困难疗效和不良反应观察

Effects and adverse reactions of prepulside and low dosage erythromycin in treating preterm infant feeding intolerance

目的:观察小剂量红霉素、西沙必利治疗早产儿喂养困难的疗效和不良反应。方法:将75例喂养困难早产儿随机分为3组,对照组(C组)常规治疗,西沙必利组(A组)及红霉素组(B组)在常规治疗基础上分别加用西沙必利和小剂量红霉素。结果:西沙必利组总有效率为88%、红霉素组总有效率为84%、对照组为52%。平均症状消失时间红霉素组及西沙必利组均较对照组缩短,两组疗效无显著性差异。结论:西沙必利、小剂量红霉素均能改善早产儿喂养困难,两者疗效对比无显著性差异。

Objective： To investigate and compaw the effects of prepulside and erythromycin in treating preterm infant feeding intolerance. Methods： 75 cases of preterm itffans with feeding intolerance were divided into three groups： A for prcpulside group. B for erythromycin group and C the control group. Results： The total effective rate of prepuside group was 88%. erythromyein group 84%, and control group 52%. The mean time to symptom disappearance of preprlside group and erythromycin group was shortor than that of the control group. And there was no signit]cant difference between the effects of prepulside group and erythmmyein group. Conclusition： Both prepuldide and low dosage erythromycin can improve preterm infant feeding intolerance, however, there is no signifieant diffreence between the effects of the two drugs.