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双孔钾通道研究进展 被引量：3

Progress in research on two-pore-domain potassium channel family
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摘要 双孔钾通道是具有4个跨膜片段(4TMS)和2个孔道结构域(2P)的钾通道亚型,按其功能可分成6类:①TWIK-1和TWIK-2,②TREK-1和TREK-2,③TRAAK,④TASK-1、TASK-2、TASK-3、TASK-4和TASK-5,⑤THIK-1和THIK-2,⑥TALK-1和TALK-2。双孔钾通道组织分布广泛,在可兴奋细胞和非可兴奋细胞中均可发现,其产生的电流是瞬时性和非失活性的,在所有膜电位时程中均有活性,且对经典的钾通道阻滞剂不敏感。
作者 董侃 陶谦民 夏强
机构地区 浙江大学医学院附属第一医院心内科 浙江大学医学院生理教研室
出处 《浙江大学学报（医学版）》 CAS CSCD 2005年第5期476-480,共5页 Journal of Zhejiang University(Medical Sciences)
关键词 钾通道 双孔钾通道 生理学 文献综述
分类号 R33 [医药卫生—人体生理学]
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参考文献27

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同被引文献51

  • 1薛军辉,张作明.流体切应力作用血管内皮系统机制的研究[J].医学争鸣,2001(S1):97-100. 被引量：2
  • 2冯红,徐文琳,战锐,钱令嘉.pEGFP-N1质粒转染乳鼠心肌细胞的分布及效率[J].中国应用生理学杂志,2005,21(1):112-114. 被引量：7
  • 3段波,徐天乐.TRP通道与信号转导[J].生物物理学报,2005,21(4):245-260. 被引量：18
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  • 10Shimkets RA,Warnock DG,Bositis CM,et al.Liddle's syndrome:heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel[J].Cell,1994,79(3):407-414.

引证文献3

二级引证文献2

浙江大学学报（医学版）
2005年 第5期

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