颌面部毛细血管母细胞瘤1例报告

Maxillary capillary hemangioblastoma: Case report

报告1例4个月龄幼儿面部毛细血管母细胞瘤病例,并复习相关文献。毛细血管母细胞瘤是组织起源未定的I级肿瘤(WHO分类),多见于小脑,发生于颌面部者鲜有报道。该病术前诊断率低,缺乏特征性临床表现及免疫标识。病理学检查可见基质细胞和丰富的毛细血管。广泛切除为其有效的治疗方法,但存在一定的复发率。肿瘤的良恶性尚存在争议。

A case of maxillary capillary hemangioblastoma in a 4-month-old infant was reported and relevant literatures were reviewed. The capillary hemangioblastoma is a WHO grade Ⅰ tumor of uncertain histogenesis. Most capillary hemangioblastomas are located in the cerebella, few are in the maxillary region. Because of lacking characteristic symptoms and immunological markers, the capillary hemangioblastoma can＇t be easily diagnosed preoperatively. Histopathologically the tumor is composed of stromal cells and abundant capillaries. Extensive surgical excision is an effective treatment method but recurrence may occur in some cases. Whether the tumor is benign or malignant is still under consideration.