维持性血液透析患者血清铁状况的调查

The Evaluation of Iron Status in Maintenance Hemodialysis Patients

目的:评价稳定的维持性血液透析患者的血清铁状况。方法:选取50例稳定的血液透析患者,在透析前测定血清铁蛋白(SF)、转铁蛋白饱和度(TSAT)、总铁结合力(TIBC),在透析后取血测定血红蛋白(Hb)、红细胞压积(HCT)。结果Hb(85.5±13.6)g/L,HCT(28.15±4.29)%,SF(297.56±213.81)ng/mL,TSAT(21.5±8.3)%,TIBC(58.46±18.49)μmol/L。绝对性缺铁占68%,功能性缺铁占20%。每天口服补充元素铁达到300 mg的患者铁缺乏占52.6%,达不到300 mg的患者铁缺乏占70.0%,差异无显著性(P>0.05)。结论:维持性血液透析患者铁缺乏较为普遍,口服补铁效果欠佳。

Objective:To evaluate iron status in maintenance hemodialysis patients.Methods:Serum Ferritin(SF)、Transferrin Saturation(TSAT)、Total Iron Binding capability(TIBC)、Hemoglobin(Hb)、Hematocrit(HCT)were measured in 50 patients undergoing maintenance hemodialyis.Results:Hb(85.5±13.6)g/L,HCT(28.15±4.29)%,SF(297.56±213.81) ng/mL,TSAT(21.5±8.3)%,TIBC(58.46±18.49) μmol/L.The absolute iron deficiency rate was 68%,the functional iron deficiency rate was20%.The rate of iron deficiency was 52.6%in patients whose oral iron supplementation reached 300mg elemental iron per day,compared with 66.7% in patients whose oral iron supplementation failed to reach that level per day(P>0.05).Conclusions:Iron deficiency was prevalent in patients undergoing hemodialysis,the efficiency of oral iron supplementation was not satisfying.