摘要
Objective： To compare the clinical efficacy of combined acupuncture and herbs with danazol in treating endometriosis. Methods： Seventy-eight patients were randomly divided into a combined acupuncture and herbs group （n= 40） and a Western medicine control group （n= 38）. Observation was made on changes in clinical symptoms, signs, serum CA125,β-EP, PGE2 and PGF2α, and adverse reaction to the medicine in the two groups. Results： The overall efficacy was similar in the two groups, but the effects on lumbosacral pain, anal downbearing distention, irregular menstruation and infertility were significantly better in the treatment group than in the control group （P（0.05）, and in the treatment group serum CA125, PGE2 and PGF2α were significantly lower and serum β-EP was significantly higher after treatment than before （P（0.05）. Conclusion： Combined use of acupuncture and herbs has a marked effect on endometriosis and the adverse reaction is lower than the control group.
目的:比较针药并用与西药达那唑治疗子宫内膜异位症(EMT)的临床疗效.方法:将78例患者随机分为针药并用治疗组(n=40)和西药对照组(n=38),观察治疗后两组患者临床症状、体征、血清CA125值、血清β-EP含量、PGE2、PGF2α的变化以及药物的不良反应.结果:两组总疗效相似,但治疗组在腰骶痛、肛门坠胀、月经不调、不孕等症状的改善方面显著优于对照组(P＜0.05),且治疗组治疗后血清CA125值较治疗前显著降低,血清β-EP含量显著升高,PGE2、PGF2α显著降低(P＜0.05).结论:针药并用治疗EMT临床疗效显著,其不良反应明显低于西药组.
