湖南省2004年药品不良反应报表统计

Statistics of 7061 ADR Report Forms during 2004 in Hunan Province

目的了解湖南省2004年ADR的发生、分布情况。方法结合Excel电子表格和手工筛选,建立ADR报表数据库,对7061份ADR报表统计患者的一般情况、引起ADR的药品、ADR表现及导致的系统一器官损害、ADR死亡病例等内容。结果ADR可发生于任何年龄,发生ADR的药物以抗微生物药最多见,ADR累及的系统-器官以皮肤及其附件的损害最多见,导致死亡的ADR以过敏性休克占绝大多数。结论抗微生物药是ADR监测的重点药物,防治药物引起的过敏性休克是防止ADR引起死亡的主要措施。

Objective To investigate the occurrence and distribution of ADR during 2004 in Hunan Province. Method By means of excel table and manual screening ,establish data base of ADR report forms.Count the patients, general conditions, drugs of causing ADR, symptoms and system-organ dammges, death cases caused by ADR. Results ADR could occur all ages. Antibiotic was the most drugs causing ADR. System-organ dammges were commonly in skin and appendixes. Allergic shock was the main cause of ADR death cases.