幽门螺杆菌感染和胃粘膜病变的关系及意义

RELATIONSHIP BETWEEN INFECTION OF HELICOBACTER PYLORI AND GASTRIC MUCOSAL LESION AND SIGNIFICANCE

为了研究幽门螺杆菌(Helicobacter Pylori,HP)感染和胃粘膜病变的关系及意义,我们复习了1342例胃镜活检的病理档案材料并进行统计学分析。结果显示:HP在慢性胃炎的阳性检出率为74.4％。HP阳性率和胃炎的活动性有关。在活动性胃炎为77.4％与非活动性胃炎的63.9％相比,差异具有显著性(P<0.05)。这个结果表明HP感染可能是慢性活动性胃炎的主要病原之一。另外,HP阳性率在肝癌为9.8％。

In order to study the relationship between infection of helicobacter pylori (HP) and gastric mucosal lesion,we reviewed 1342 pathological archives of biopsies taken by gastroscopy and analyzed statistically. The results revealed that HP positive rate was 74. 4% in chronic gastritis and correlated with the activity of chronic gastritis. The difference between active and non-active gastritis was statistically significant(P<0. 05). This investigation indicated the infection of HP may be an important cause inducing the chronic active gastritis. HP positive vate was 9. 8% in gastric cancinoma.