摘要
对144例血液病患者HBV和HCV感染状况进行调查,HBsAg、抗-HBc和抗-HCV检出率分别为9.72%、36.81%及24.31%,而健康对照组分别为12.03%、46.30%和0.93%。HCV感染率与年龄、性别无关,但与受血史,受血次数密切相关。抗HCV阳性者血清ALT水平明显高于抗-HCV阴性者,HBV/HCV重叠感染时ALT升高尤为明显。本组调查提示输血及应用血液制品是血液病患者感染HCV的重要途径。
A prevalence study on Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infection in 144 patients with hemopathy was carried out, using an enzyme linked immunosorbent assay (ELISA). The HBsAg, HBeAb and anti-HCV positive rates in sera of these patients were 9.72%, 36.81% and 24.31% respectively, comparing with data from healthy control subjects, 12.03%, 46.30% and 0.93% respectively. No correlation between HCV infection and patient's age or sex was noticed. Nevertheless the incidence of HCV infection was closely related to the history and the frequency of blood transfusion. The ALT level in sera of patients with HCV infection was higher than that of patients without HCV infection. The ALT level in sera was the highest in patients su perinfected with HBV and HCV. Our results suggested that blood transfusion and receiving blood products were important routes of HCV transmission in patients with hemopathy.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
1996年第2期74-76,共3页
Chinese Journal of Epidemiology
基金
国家八五攻关项目