助孕儿与自然受孕儿生长发育对比分析

The development in children born after assisted reproduction treatment

目的比较助孕儿与自然受孕儿生长发育的差异,探讨助孕技术对婴儿生长发育的影响。方法对2001年1月至2004年7月期间在北京大学深圳医院儿童保健门诊随访的助孕儿(47例)和自然受孕儿(47例)进行新生儿甲状腺功能低下、苯丙酮尿症筛查,按儿童保健常规检查随访1年,包括身长、体重、血常规及丹佛发育筛选测验(DDST);统计、分析各项指标的差异。结果助孕儿与自然受孕儿新生儿甲状腺功能低下、苯丙酮尿症筛查均正常;在1岁内体格发育、DDST筛查及6、12月龄血红蛋白差异均无显著意义(P>0.05)。结论助孕儿(1岁内)生长发育与自然受孕儿比较差异无显著意义,但远期的生长发育尚需进一步追踪研究。

Objective To compare development in children after ART with that in natural way children. Methods Children who are examined in Department of preventive health care of Beijing university Shenzhen hospital during January 2001 and July 2004 were divided two groups. The test group： 47 children born after ART, the control ：47 children born in natural way. Height and weight were assessed by WHO criterion. Both hypothyroidism and phenylketonuria were screened in two groups. The blood test was done in 6 and 12 month old, then statistics were analysed. Results There was no difference in hypothyroidism,phenylketonuria, ferrohemoglobin,development within a year old,and DDST screening between two groups. Conclusions There is no difference within a year old between children born after ART and children in natural way. But the difference of development in the future would be studied further.