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MDMA(摇头丸)对小鼠LD_(50)的测定及其毒性作用 被引量：4

Measurement of Rat LD50 to Methylenedioxymethamphetamine(MDMA) and its Toxicity
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摘要 MDMA(3,4亚甲基二氧甲基苯丙胺)属于苯丙胺类兴奋剂中的一种特殊类型,俗名“摇头丸”。该药传入我国内地之后成为严重危害人类健康的新型毒品。本文通过灌胃和腹腔注射两种方法测定MDMA的半数致死量(LD50),并研究它对小鼠的毒性作用。研究表明,MDMA对昆明系小鼠经灌胃给药的LD50为27.35mg/kg体重,腹腔注射的LD50为42.85mg/kg体重,试验鼠表现出高度兴奋、尖叫和冲撞,最后因呼吸麻痹而死亡。此研究有助于人们进一步认识该毒品的毒性作用及其对人体健康的危害。
作者 周丽萍 贺东生
机构地区 华南农业大学兽医学院
出处 《广东畜牧兽医科技》 2005年第5期41-43,共3页 Guangdong Journal of Animal and Veterinary Science
关键词 MDMA 小鼠 LD50
分类号 S854.43 [农业科学—临床兽医学]
  • 相关文献

参考文献5

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二级参考文献25

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共引文献12

同被引文献55

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引证文献4

二级引证文献17

广东畜牧兽医科技
2005年 第5期

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