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β地中海贫血基因治疗进展 被引量:2

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作者 李文益 孟哲
出处 《中国小儿血液》 2005年第4期185-187,共3页 China Child Blood
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  • 1May C, Rivella S, Challegarl J, et al. Therapeutic haemoglobin synthesis in β- thalassemia mice expressing lentivirus- encoded human β- globin.Nature, 2000;406:82.
  • 2Imren S, Payen E, Westerman KA, et al. Permenent and panerythroid correction of murone β - thalassemia by multiple lentiviral integration in HSCs. PNAS, 2002; 94:14380.
  • 3Stathopulos PB. Taking the good out of the bad: lentiviral - based gene therapy of the hemoglobinopathies. Biotechnol Adv, 2003 Sep;21(6):513.
  • 4Puthenveetil G, Scholes J, Carbonell D, et al. Successful correction of the human beta - thalassemia major phenotype using a lentiviral vector.Blood, 2004; 104:3445.
  • 5Hanawa H, Hargrove PW, Kapes S, et al. Extended β - globin locus control elements promote consistent expression of a γ - globin lentiviral vector in murine β - thalassemia. Blood, 2004;104:2281.
  • 6Bradai M, Abad MT, Pissard S, et al. Hydroxyurea can eliniate transfuse requirements in children with severe β - thalassemia. Blood, 2003; 102:1529.

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