变应原皮试与血清特异性IgE检测诊断变应性鼻炎

Diagnosis of Allergic Rhinitis with Allergen Skin Test and Specificity IgE

目的探讨体内变应原皮试和体外特异性IgE检测的临床价值.方法采用单价花粉变应原浸液对80例变应性鼻炎(AR)花粉症患者作过敏原皮试检查;同时进行血清特异性IgE含量的测定.结果80例花粉变应原皮试阳性患者血清特异性IgE明显异常,两种检查方法的总阳性率81.4%～66.7%,阳性一致率95.0%～77.3%,差异有显著性(P＜0.01).结论表明两种检测方法的抗原特异性高度一致,对AR病因诊断、减敏治疗中变应原种类的选择及预防等均有较高的临床应用价值.

Objective To explore the kinds and rules of the air - borne ascendancy sensitizing pollen, and the relationship to the allergic rhinitis（AR）. Methods From 2003, 11 to 2004,11, surveying the air - borne pollen by gravitational measure method and assaying 80 cases AR patients with allergen skin test by the monovalent pollen allergen different from foretime and investigated the episode season. The positive cases were examined through the serum specificity IgE. Results We surveyed pollen 26124 grains in the whole year. Belong 25 family and 42 genera, the fluttered pollen were seen the whole year with two peaks of 3 ～ 6 months and 8 ～ 9 months. Which was affected by temperature and wind force; the episode season of seasonal allergic rhinitis was agreement to the climax of airborne pollen. In 80cases,the positive rate is 81.4% ～ 66. 7% ,the positive accordance rate 95.0% ～77.3 % , theres obvious difference （ P 〈 0.01 ）. Conclusion Our research will provide credible data for epidemiology study of local and domestic area, and it has important clinical guidance function and practical value to prevention, diagnosis and treatment of AR.