病毒性肝炎患者血清庚型肝炎RNA的检测

Detection of RNA of Hepatitis G Virus in Serum of Patients with Hepatitis.

目的:了解A^C型及非A~非E型病毒性肝炎患者庚型肝炎病毒(HGV)的感染情况。方法:对103名病毒性肝炎患者采用ELISA和RT-PCR检测HGV-RNA,根据不同病原类型和不同临床类型的肝炎患者对庚型病毒的感染情况进行分析。结果:不同病原肝炎患者中,乙型肝炎患者HGV-RNA的阳性率为33.3%,明显高于其他类型的肝炎患者(P<0.01),在不同临床类型的肝炎患者中,慢性肝炎患者HGV-RNA的阳性率为32.6%,明显高于其他临床类型的肝炎患者(P<0.01)。结论:HGV是病毒性肝炎的病原之一,在病毒性肝炎患者中感染率较高,并常与其他类型的肝炎病毒合并感染。

Objectives：To study the infection of hepatitis G virus among patients with hepatitis. Methods：The serum of 103 hepatitis pa- tients was examined by ELLSA and RT-PCR, and the results were analyzed according to the virus type and the clinic type. Results：The infection rate of HGV among patients with hepatitis B was 33.3%, which was higher than patients with other type hepatitis （P 〈 0.01 ）. The infection rate of HGV among patients with chronic hepatitis was 32.6%, which was higher than patients with other clinic types（ P 〈 0.01 ） .Conclusions：HGV was one of causes of viral hepatitis. The infection rates among patients with viral hepatitis higher, and HGV was often complicated infection with other hepatitis virus.