108例HIV感染者/AIDS病人临床分析

Clinical analysis of 108 cases with HIV/AIDS

目的了解艾滋病重点村艾滋病病毒(H IV)感染者和获得性免疫缺陷综合征(AIDS)临床表现的特点,及抗逆转录病毒治疗(ART)的效果。方法对H IV感染者和AIDS病人的流行病学和临床资料加以归纳总结。结果AIDS病人72例。28例进行了丙肝抗体检测,仅1例阴性。69例AIDS病人进行了抗逆转录病毒治疗,服药后34例患者出现了不同程度的不良反应,16例退出治疗,50例AIDS病人坚持抗病毒治疗半年至1年半临床症状改善率94%结论ART确实大大减轻了患者的临床症状,但不良反应较大,影响了患者的服药依从性,部分病人出现耐药,药物的组合和选择均受到限制,探索适合贫困地区抗逆转录病毒治疗的新路已是当务之急。

Aim To understand clinical characteristic of HIV/AIDS in one AIDS village in Fuyang,and determine the effect of the ART （antiretroviral therapy）. Methods Analysis the epidemiological and clinical of 108 cases with HIV/AIDS. Results 69 AIDS cases were treated with ART. Side effects were found in 34 cases. 16 cases stopped treatment on the half way. 50 cases persisted in treatment. Clinical symptoms were well improved （94%） ,CD4 cell counts were risen （66%） ,and HIV viral loads were descended l0 times and undeteetable （62%）. 16 cases had resistance. Conclusion It is very important to protect the high risk groups and intervene in high risk behavior. ART （antiretroviral therapy） is the most effective method in curing HIV/AIDS, and its clinical effectiveness is closely related to the clinical compliance.